Prevalence and risk factors for prenatal parasitic infections and anaemia among pregnant women in Kaduna State, Nigeria
https://dx.doi.org/10.4314/njpar.v44i1.23
Keywords:
Kaduna State, antenatal care, pregnant women, parasitic infections, AnaemiaAbstract
In developing nations, anaemia is one of the most prevalent medical conditions. It has long been known that parasite infection during pregnancy is one of the main causes of anaemia and an elevated risk of maternal mortality. To ascertain the prevalence and risk factors related to parasite infections and anaemia among pregnant women receiving prenatal care in some selected public health facilities in Kaduna State, Nigeria, an eleven-month cross-sectional study of 180 consenting pregnant women was conducted from February to December 2017. A standardized questionnaire was used to interview the sampled pregnant women. Stool and blood samples of each consented pregnant woman were collected. Formal-ether sedimentation technique, thin and thick blood smears and haematocrit packed cell volume capillary methods were used to screen intestinal helminth parasites, plasmodium species and Packed Cell Volume (PCV) respectively. The result obtained showed parasitic infections prevalence of 102(56.7%) among the study population. Prevalence of Plasmodium species, hookworm, Ascaris lumbricoides and those with co-infection all occurred at 47.2%, 16.7%, 17.8% and 25.0% respectively. Age, educational level, trimester and parity were all significant predictors of Plasmodium species prevalence (p<0.005). Similarly, parity and educational level were significantly (p<0.005) associated with the prevalence of intestinal parasites and co-infection. Anaemia was present in 40.0% of the examined pregnant women. Trimester and educational level were highly significant (p<0.001) predictors of anaemia among the sampled pregnant women. Plasmodium species were the most common parasitic species associated with anaemia as 43.1% of Plasmodium species-infected pregnant women had anaemia compared to those with intestinal helminth infection (30.6%) and co-infection (13.3%). However, statistical analysis revealed a significant association (p<0.05) between the prevalence of anaemia and intestinal helminth infection. Therefore, measures such as improved sanitation and health education are needed to lessen the prevalence of parasitic infections and parasite-related anaemia in the study area.
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References
Tsoka-Gwegweni, J. M. and Ntombela, N. P. (2014). A double load to carry: parasites and pregnancy. South African Journal of Infectious Disease, 29(2):52-55.
Olatunbosun, O. A., Abasiattai, A. M., Bassey, E. A., James, R. S., Ibanga, G. and Anyiekere, M. (2014). Prevalence ofanaemia among pregnant women at booking in the University of Uyo Teaching Hospital, Uyo, Nigeria. Biomedical Research International, 2014: 849080. doi:10.1155/2014/849080
Buhari, H., Imoru, M. and Erhabor, O. (2016) Anaemia in Pregnant Women of Sokoto Residents in North Western Nigeria. Journal of Blood Disorders and Transfusion 7: 366. doi:10.4172/2155-9864.1000366
Derso, A., Nibret, E. and Munshea, A. (2016). Prevalence of intestinal parasitic infections and associated risk factors among pregnant women attending antenatal care center at Felege Hiwot Referral Hospital, northwest Ethiopia. BMC InfectiousDiseases 16:530. DOI 10.1186/s12879-016-1859-6
Agu, P. U., Ogboi, J. S., Akpoigbe, K., Okeke, T. and Ezugwu, E. (2013). Impact of Plasmodium falciparum and Hookworm infections on the Frequency of Anaemia in Pregnant Women of Rural Communities in Enugu Southeast Nigeria. The Pan Africa Medical Journal, 14(27). http://www.panafrican-med-journal.com/content/larticle/14/27/full/.
Tegegne, Y., Asmelash, D., Ambachew, S., Eshetie, S., Addisu, A. and Zeleke, A. J. (2019). The Prevalence of Malaria among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis. Journal of Parasitology Research, 2019:8396091.https://doi.org/10.1155/2019/8396
Njua-Yafi, C., Achidi, E. A., AnchangKimbi, J. K., Apinjoh, T. O., Mugri, R. N., Chi, H. F., Tata, R. B., Njumkeng, C., Nkock, E. N. and Nkuo-Akenji, T. (2016). Malaria, helminths, co-infection and anaemia in a cohort of children from Mutengene, southwestern Cameroon. Malar
Journal 15:69. DOI 10.1186/s12936-016-1111-2
Feleke, B. E. and Jember, T. H. (2018). Prevalence of helminthic infections and determinant factors among pregnant women in Mecha district, Northwest Ethiopia: a cross-sectional study. BMC Infectious Diseases 18:373. https://doi.org/10.1186/s12879-018-3291-6
Mengist, H. M., Zewdie, O., Belew, A. (2017) Intestinal helminthic infection and anemia among pregnant women attending antenatal care (ANC) in East Wollega, Oromia, Ethiopia. BMC Research Notes 10:440. DOI 10.1186/s13104-017-2770-y
Fusieni, G., Edoh, D., Gumah, B. K. and Dave, K. (2013). Plasmodium and intestinal helminths distribution among pregnant women in the Kassena-Nankana District of Northern Ghana. International Journal of Nematology and Entomology, 1(3): 037-041.
http://www.internationalscholarsjournals.or g
Al-Hamairy, A. K. A., Al-Mosaui, A. M. A. and Al-Rubaea, A. H. M. (2013). Prevalence of parasitic infection and relationship with anemia in Al-doullab Village, Babylon Province, Iraq. Egyptian Journal of Experimental Biology (Zoology) 9(2): 231 – 236. http://www.egyseb.org
Melku, M., Addis, Z., Alem, M. and Enawgaw. B. (2014). Prevalence and Predictors of Maternal Anemia during Pregnancy in Gondar, Northwest Ethiopia: An Institutional Based Cross-Sectional Study. Anaemia2014: 108593.http://dx.doi.org/10.1155/2014/108593
Nnah, E. W. and Kasso, T. (2017) The prevalence of malaria and helminth infection in pregnancy at booking and their relationship to anaemia at the University of Port Harcourt Teaching Hospital, Southern Nigeria. International Journal of Tropical Disease and Health, 28(4): 1-9. http://www.sciencedomain.org/reviewhistory/22823
Naing, C., Whittaker, M. A., Nyunt-Wai, V. Reid, S. A., Wong, S. F. Mak, J. W. and Tanner, M. (2017) Malaria and soiltransmitted intestinal helminth co-infection and its effect on anemia: A meta-analysis. Transactions of the Royal Society of Tropical Medicine and Hygiene, 107: 672–683.Doi:10.1093/trstmh/trt086
Tesfaye, D. J., Beshir, W. G., Dejene, T. and Tewelde, T. (2015). Prevalence of intestinal helminthiases and associated factors among pregnant women attending antenatal Clinic of Nigist Eleni Mohammed Memorial Hospital, Hossana, Southern Ethiopia. Open Access Library Journal 2: e 1 6 6 0 .http://dx.doi.org/10.4236/oalib.1101660
Adeline, I. A. and Eme, O. I. (2015). Census politics in Nigeria: An examination of 2006 population census. Journal of Policy and Development Studies, 9(3): 47-72. DOI: 10.12816/0011166.
Alli, J. A., Okonko, I. O., Kolade, A. F., Nwanze, J. C., Dada, V. K. and Ogundele, M. (2011). Prevalence of intestinal nematode infection among pregnant women attending pregnant clinic at the University College Hospital, Ibadan, Nigeria. Advances in Applied Science Research 2(4): 1-13.http://www.pelagiaresearchlibrary.com
Babamale, O. A., Ugbomoikoa, U. S. and Heukelbachb, J. (2018). High prevalence of Plasmodium falciparum and soil-transmitted
helminth co-infections in a periurbancommunity in Kwara State. Nigeria Journal of Infection and Public Health 11: 48–53. http:// www.elsevier.com/locate/jiph
Joseph, R., Chessed, G., Daniel, L.,Haruna, Y., Demshemino, M. P. H. and Bagula, R. L. (2017). Prevalence of malaria and geohelminth co-infection among pregnant women at the Federal Medical Centre and Specialist Hospital, Yola, Adamawa State, Nigeria. Journal of Applied
Science and Environmental Management, 21(3): 469- 473.https://dx.doi.org/10.4314/jasem.v21i3.7
Yatich, N. J., Yi, J., Agbenyega, T., Turpin, A., Rayner, J. C. Stiles, J. K. Ellis, W. O., Funkhouser, E., Ehiri, J. E., Williams, J. H. and Jolly, P. E. (2009). Malaria and intestinal helminth co-infection amongpregnant women in Ghana: Prevalence and risk factors. American Journal of Tropical
Medicine and Hygiene, 80(6): 896–901. Doi: hhtps://doi.org/10.4269/ajtmh.2009.80.896
Getachew, M., Tafes, K., Zeynudin, A. and Yewhalaw, D. (2013). Prevalence of soiltransmitted helminthiasis and malaria coinfection among pregnant women and risk factors in Gilgel Gibe dam Area, Southwest Ethiopia. BMC Research Notes 6: 263. http://www.biomedcentral.com/1756-0500/6/263
Agboli, E., Tay, S. C. K., Obirikorang, C. and Aidoo, E. Y. (2015). Malaria and intestinal parasites in pregnant and nonpregnant women: a comparative study at the University Hospital, Kumasi, Ghana. Journal of Medical and Biomedical Sciences, 4(3): 31-35. doi:http://dx.doi.org/10.4314/jmbs.v4i3.5
Obeagu, E. I., Odo, M. C., Nanaebo, Q. B., Emelike, C. U. (2014). Impact of Plasmodium falciparum malaria and hookworm infection on anaemia among pregnant women of Ikwuano LocalGovernment Area, Abia State, Nigeria. International Journal of Current Microbiology and Applied Sciences, 3(1): 104-111. http://www.ijcmas.com
Akinbo, F. O., Olowookere, T. A., Okaka, C. E. and Oriakhi, M. O. (2017). Coinfection of malaria and intestinal parasites among pregnant women in Edo State, Nigeria. Journal of Medicine in the Tropics19: 43-48. http://www.jmedtropics.org
Bawa, J. A., Auta, T. and Liadi, S. (2014). Prevalence of malaria: knowledge attitude and cultural practices of pregnant women in
Katsina metropolis, Nigeria, European Scientific Journal, 10(21): 148-167. https://www.researchgate.net/publication/268746412.
Dimejesi, I. B., Umeora, O. U., Egwuatu, V. E. (2014). Prevalence and pattern of soiltransmitted helminthiasis among pregnant women in a tertiary health facility, southeast Nigeria, African Journal of Medical and Health Sciences, 13(1) 56 - 61.http://www.ajmhs.org
Tay, S. C. K., Nani, E. A. and Walana, W. (2017). Parasitic infections and maternal anaemia among expectant mothers in the Dangme East District of Ghana. BMC Research Notes 10:3. DOI 10.1186/s13104-016-2327-5.
Osazuwa, F., Ayo, O. M. and Imade, P. A.(2011) Significant Association betweenintestinal helminth infection and anaemia burden in children in rural communities of Edo state, Nigeria. North American Journal of Medical Sciences 3: 30-34. Doi:10.4297/najms.2011.330
Wekesa, A., Mulambalah, C., Muleke, C. and Odhiambo, R. (2014) Intestinalhelminth infections in pregnant women attending pregnant clinic at Kitale district hospital, Kenya. Journal of Parasitology Research, 2014: 823 – 923. http://dx.doi.org/10.1155/2014/823923.
Iwunze, J. I. and Amaechi, A. A. (2019). Malaria and Intestinal Helminthes Coinfection among Pregnant Women Attending Antenatal Clinic in Obowo Imo State, Nigeria. International Journal of Medical Science in Clinical Research and Review 2(6): 143-153. http://www.ijmscrr.in
Jufar, A. H. and Zewde, T. (2014).Prevalence of Anemia among Pregnant Women Attending Antenatal Care at Tikur Anbessa Specialized Hospital, Addis Ababa Ethiopia. Journal of Hematology and Thromboembolic Diseases, 2: 125. doi: 10.4172/2329-8790.1000125
Mohammed, Y. G. and Emmanuel, A. U. (2013). The pattern of anaemia in Northern Nigerian pregnant women. Journal ofMedicine and MedicalSciences 4: 319-323. doi: 10.14303/jmms.2013.097
Paul, B. A., Lucy, I., Mary, D. N., Godwin, A. O., Seljul, R. M., Olugbenga, O. T., Kurgnan, P. J., Nneka, O. V., Seye, O. J., Ehi, A. W., Ojoma, A. V., Kate, A. E. and Olufunmilola, O. O. (2016). Prevalence of Anaemia in Pregnancy Among Women Visiting Antenatal Clinic in Bingham
University Teaching Hospital Jos, Nigeria. Clinical Medicine Research 5(3): 52-62. doi: 10.11648/j.cmr.20160503.17
Bukar, M., Audu, B. M., Yahaya, U. R. and Melah, G. S. (2008). Anaemia in pregnancy at booking in Gombe, North-eastern Nigeria. Journal Obstetrics Gynaecology, 28: 775-778. doi: 10.1080/01443610802463835
Ndukwu, G. U. and Dienye, P. O. (2012). Prevalence and socio-demographic factors associated with anaemia in pregnancy in a primary health centre in Rivers State,Nigeria. African Journal of Primary Health Care and Family Medicine, 4(1): 328. http:// dx.doi.org/10.4102/phcfm.v4i1.328
Ahenkorah, B., Nsiah, K. and Baffoe, P.(2016). Sociodemographic and Obstetric Characteristics of Anaemic Pregnant Women Attending Antenatal Clinic in Bolgatanga Regional Hospital Scientifica 2016: 4687342. http://dx.doi.org/10.1155/2016/4687342
Ojukwu, O. M., Ezem, B. U., Nzeribe, E. A., Okorochukwu, B. C., Onyegbule, O. A. and Bamayi, N. U. (2018). Determinants and Pattern of Anaemia in Pregnancy at Booking in Federal Medical Centre Owerri, South-East, Nigeria. International Journal of Tropical Disease and Health 33(2): 1-13. http://www.sciencedomain.org/reviewhistory/27347
Hoque, A. K., Kader, S. B., Horque, E. and Mugero, C. (2006). Prevalence of anaemia in pregnancy at Greytown, South Africa. Tropical Journal of Obstetrics Gynaecology, 23: 3. doi: 10.4314/tjog.v23i1.14554
Onwuhafua, P. I., Ozed-Williams, I. C., Kolawole, A. O., Zayyan, M. S. and Adze, J. (2018). Prevalence of anaemia in the antenatal booking population at Ahmadu Bello University teaching hospital, Kaduna, Nigeria. Port Harcourt Medical Journal 12(1): 44-48. DOI:10.4103/phmj.phmj_32_17
Anchang-Kimbi, J. K., Nkweti, V. N., Ntonifor, H. N., Apinjoh, T. O., Chi, H. F., Tata, R. B. and Achidi, E. A. (2017). Profile of red blood cell morphologies and causes of anaemia among pregnant women at first clinic visit in the mount Cameroon area: a prospective cross-sectional study. BMC Research Notes 10: 645. DOI 10.1186/s13104-017-2961-6
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